Phase II Clinical Trial of Flu-Bu-Mel-E (Fludarabine, Busulfan, Melphalan and Etoposide) as Conditioning Regimen for Patients With Lymphoid Malignancies Undergoing Allogeneic Stem Cell Transplantation
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 2
SUMMARY
In this phase II clinical trial, we evaluate the efficacy and feasibility of conditioning regimen of fludarabine 150mg/m2, busulfan 9.6mg/kg, melphalan 100mg/m2 and etoposide 800mg/m2 in patients with lymphoid malignancies.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 16
Maximum Age: 60
Healthy Volunteers: f
View:
• lymphoid malignancies
• donor available: HLA matched sibling, unrelated donor or haplo-identical related donor.
• patients with ECOG \<3
Locations
Other Locations
China
Blood & Marrow Transplantation Center, RuiJin Hospital
RECRUITING
Shanghai
Contact Information
Primary
Jiong Hu
hj10709@rjh.com.cn
86-21-64370045
Backup
Jieling Jiang
jjl12223@rjh.com.cn
86-21-64370045
Time Frame
Start Date: 2021-01-01
Estimated Completion Date: 2024-12-01
Participants
Target number of participants: 23
Treatments
Experimental: treatment arm
treatment arm
Related Therapeutic Areas
Sponsors
Leads: Shanghai Jiao Tong University School of Medicine